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March 28, 2025What Is Syphilis?

Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. The disease is very contagious, hence causing severe health implications in case it is left untreated. Despite medical researchers' efforts, syphilis is still a public health issue since it is easily transmissible and could be very severe. In the following article, we shall discuss the causes, symptoms, diagnosis, treatment, prevention, and long-time effects of the disease. Visit Smart Choice Clinic for more details.
What causes Syphilis?
Syphilis is mainly passed through sexual contact. This may include vaginal, anal, or oral sex. The disease can also be transferred from an infected mother to her baby during childbirth. This condition is called congenital syphilis. The bacteria enter the body through mucous membranes or open cuts on the skin. Blood transfusions or needle-sharing among drug users can also cause syphilis. However, due to strict medical screening, such cases are now rare.
Symptoms of Syphilis

Syphilis appears in four different stages; each stage has symptoms. Diagnostic and therapeutic attention should be taken at this stage.
Primary Stag
- Throughout the infection site (genitals, anus, or mouth), painless sores or chancres develop.
- Sores may heal in a period of 3-6 weeks even if not treated.
- In most cases, patients fail to see a doctor as it is not painful.
Secondary Stage
- Generalized skin rash, which frequently occurs on palms and soles of the feet.
- Flu-like symptoms include fever, swollen lymph nodes, sore throat, and fatigue.
- Wart-like lesions in moist areas of the body, like the genitals or mouth.
- Patchy hair loss and muscle aches.
- It may disappear, and then a latent stage ensues.
Latent Stage
- There are no observable symptoms, but the bacteria persist in the body.
- This stage may persist for decades and may develop into tertiary syphilis if not treated.
Tertiary Stage
- Severe complications that involve major organs such as the heart, brain, and nervous system.
- Symptoms may include paralysis, blindness, memory loss, and dementia.
- Can be fatal if left untreated, leading to neurosyphilis and cardiovascular syphilis.
How is Syphilis Diagnosed?
Syphilis is diagnosed with several tests, which include:
- Blood tests: The test detects antibodies against Treponema pallidum.
- Dark-field microscopy: It identifies bacteria from an active syphilitic sore.
- Lumbar puncture (spinal tap): Done in cases suspected of neurosyphilis for the examination of cerebrospinal fluid.
- Physical examination: Doctors may look for characteristic sores and rashes of syphilis.
Treatment for Syphilis
- Penicillin injection: It is the best and most widely recommended treatment for all stages of syphilis.
- Alternative antibiotics: Doxycycline or azithromycin are prescribed in patients allergic to penicillin.
- Follow-up blood tests: To ensure the infection is fully removed.
- Partner treatment: The sexual partners must also be tested and treated to avoid reinfection.

Complications of Untreated Syphilis
If the disease is not treated, it can lead to severe health complications, including the following:
- Neurological disorders: Stroke, hearing loss, vision problems, and movement disorders.
- Cardiovascular damage: Aneurysms, heart valve diseases, and blood vessel inflammation.
- Increased risk of HIV: Open syphilitic sores increase the susceptibility of HIV into the body.
- Congenital syphilis: It may cause stillbirth, birth defects, premature delivery, and developmental problems in newborns.
- Gummas: These are soft, tumor-like lesions on the skin, bones, and other internal organs.
How to Prevent Syphilis
To decrease the chances of acquiring syphilis, some of the measures are as follows:
- Use condoms: The correct and consistent use of condoms prevents the transmission.
- Regular STI testing: Screening regularly is essential to detect it early and cure it.
- Have fewer sexual partners: The less number of partners one has reduces the risk of exposure.
- Pregnancy testing: Pregnant women should be tested for syphilis to avoid congenital syphilis.
- Avoid sharing needles: Drug users should adopt harm reduction strategies.
- Early treatment: Early treatment helps prevent the advancement to the final stages.
Syphilis at the Global Level
Syphilis is still a global health issue, especially in low-income areas where access to healthcare is minimal. The WHO reports that millions of new cases of syphilis are diagnosed every year, and congenital syphilis is one of the leading causes of stillbirths worldwide. Public health programs emphasize education, increased STI testing, and better access to antibiotics to reduce the spread of syphilis.
Living with Syphilis: Managing Long-Term Effects

For patients diagnosed with syphilis, timely interventions are necessary to curb severe sequelae. With established complications, the management of symptoms in a patient depends on changes in lifestyle and medical help such as:
- Neurological rehabilitation: Therapy for motor dysfunction and cognitive impairments.
- Cardiovascular care: Drug therapy and modification of lifestyle to promote heart health.
- Mental health support: Counseling and therapy for handling emotional disturbances.
Conclusion
Syphilis is a serious but treatable infection, and immediate medical care should be sought. If the symptoms of syphilis are recognized early and sought for treatment, severe health complications may be prevented. Practicing safe sex, frequent STI screenings, and public awareness about syphilis can keep its prevalence at minimum rate. If you suspect exposure to syphilis or need expert care, immediately consult a healthcare professional. For more information and support, visit Smart Choice Clinic.